[Snake]

Honestly, all weapons should have this treatment except Fists, Tomes and Guns.

You can have another hand behind a Dagger's handle to force it to pierce deeper, or hold it with two hands. (And knives are often used in dual-wielding thanks to Twin Dance, so mono-daggers can have a role.)

You obviously can effectively use a Bow better with two hands. (I never understood how you could even shoot with your hand occupied.)

Etc.